The top 25 questions are:
- What Is the Universe Made Of?
- What is the Biological Basis of Consciousness?
- Why Do Humans Have So Few Genes?
- To What Extent Are Genetic Variation and Personal Health Linked?
- Can the Laws of Physics Be Unified?
- How Much Can Human Life Span Be Extended?
- What Controls Organ Regeneration?
- How Can a Skin Cell Become a Nerve Cell?
- How Does a Single Somatic Cell Become a Whole Plant?
- How Does Earth's Interior Work?
- Are We Alone in the Universe?
- How and Where Did Life on Earth Arise?
- What Determines Species Diversity?
- What Genetic Changes Made Us Uniquely Human?
- How Are Memories Stored and Retrieved?
- How Did Cooperative Behavior Evolve?
- How Will Big Pictures Emerge from a Sea of Biological Data?
- How Far Can We Push Chemical Self-Assembly?
- What Are the Limits of Conventional Computing?
- Can We Selectively Shut Off Immune Responses?
- Do Deeper Principles Underlie Quantum Uncertainty and Nonlocality?
- Is an Effective HIV Vaccine Feasible?
- How Hot Will the Greenhouse World Be?
- What Can Replace Cheap Oil -- and When?
- Will Malthus Continue to Be Wrong?
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